Over-the-counter ibuprofen is labeled to treat fever and menstrual cramps primary dysmenorrhea. An injectable form of ibuprofen called NeoProfen is used to treat patent ductus arteriosus PDA , a type of heart defect, in premature infants.
They both block cyclooxygenase COX enzymes to control inflammation and reduce pain in those with arthritis. However, the effects of etodolac last slightly longer. Therefore, some people may prefer etodolac for its lower-frequency dosing. In a double-blind study comparing etodolac and ibuprofen , 1, patients with rheumatoid arthritis were given either mg of etodolac twice daily, mg of etodolac twice daily, or mg of ibuprofen four times daily.
Both dosages of etodolac were found to be similar in effectiveness to the ibuprofen dosage. In terms of side effects, those taking etodolac experienced less indigestion, rash, and stomach bleeding than those taking ibuprofen. However, this may be related to the amounts of drug patients were given. While no other clinical trials have directly compared etodolac and ibuprofen, different studies have compared other NSAIDs to etodolac or ibuprofen.
One meta-analysis found that the maximum daily dose of diclofenac is more effective than the maximum daily doses of ibuprofen, naproxen, and celecoxib but the lowest effective dose of NSAIDs is always recommended. Another meta-analysis found that certain NSAIDs like piroxicam and azapropazone have a high risk of toxicity while low-dose ibuprofen has a low risk of toxicity.
A doctor or healthcare provider can provide the appropriate medical advice for specific medical conditions. Generic etodolac tablets are usually covered by Medicare and insurance plans. If you have medical conditions like arthritis, insurance plans will likely cover etodolac for pain. Since ibuprofen is available over-the-counter, some forms may not be covered by insurance plans. However, most Medicare Part D and insurance plans should cover prescription-strength ibuprofen tablets depending on the treatment regimen.
In general, ibuprofen is more affordable than etodolac. Use a SingleCare coupon for ibuprofen if you have a prescription from your healthcare provider. The most common side effects of NSAIDs, including etodolac and ibuprofen, are nausea, indigestion dyspepsia , constipation, diarrhea, and abdominal or stomach pain.
Other than gastrointestinal side effects, NSAIDs can also cause dizziness, swelling in the hands or feet edema , headache, rash, and ringing in the ears tinnitus. Most side effects of etodolac and ibuprofen are mild and go away on their own. Serious side effects of NSAIDs may include allergic reactions, such as severe rash or anaphylaxis, from active or inactive ingredients.
Other serious side effects include gastrointestinal adverse effects such as stomach bleeding and peptic ulcers. Drinking alcohol when taking this medication can increase your risks of stomach bleeding and stomach ulcers. For people with high blood pressure: This medication may cause you to develop high blood pressure. If you already have high blood pressure, it may worsen your condition or increase your chances of having a heart attack or stroke.
For people with heart failure: This medication may cause you to retain water, which can cause swelling in your arms, legs, hands, or feet. This may worsen your heart failure. For people with kidney disease: This medication may cause damage to your kidneys if you use it for a long time. If you take this medication and you begin to have trouble breathing, get medical attention right away. For pregnant women: Etodolac is a category C pregnancy drug.
That means two things:. It can cause harm by affecting the heart and blood vessels of the fetus. If it does, it may cause side effects in a child who breastfeeds. You may need to decide whether to stop nursing or stop taking this medication. For seniors: People aged 65 years or older should use caution when taking this medication. Your kidneys may not work as well, which could make it harder to remove this drug from your body.
This increases your risk of side effects. Your doctor may monitor your kidneys regularly. This dosage information is for etodolac oral tablet. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Etodolac oral tablet may be used for short-term or long-term treatment. If you take this medication for short-term pain or juvenile arthritis, you may only take it for a short amount of time. If you take it for rheumatoid arthritis or osteoarthritis, you may take it short term or long term. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow?
What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names. Swallow the extended-release tablets whole; do not split, chew, or crush them. Other uses for this medicine. What special precautions should I follow? Before taking etodolac, tell your doctor and pharmacist if you are allergic to etodolac, aspirin or other NSAIDs such as ibuprofen Advil, Motrin and naproxen Aleve, Naprosyn , any other medications, or any of the inactive ingredients in etodolac tablets, capsules, or extended-release tablets.
Ask your pharmacist for a list of inactive ingredients. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. If you become pregnant while taking etodolac, call your doctor. Etodolac may harm the fetus and cause problems with delivery if it is taken around 20 weeks or later during pregnancy.
Do not take etodolac around or after 20 weeks of pregnancy, unless you are told to do so by your doctor. Do not take this medication for a longer period of time or at a higher dose than recommended by your doctor. Unless your doctor tells you otherwise, continue your normal diet. Etodolac may cause side effects. Food and Drug Administration. Brukinsa prescribing information. Updated November Updated November 15, Updated July Idiopathic constriction of the fetal ductus arteriosus: three cases and review of the literature.
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